Ozone in Medicine. The Low‐Dose Ozone Concept and Its Basic Biochemical Mechanisms of Action in Chronic Inflammatory Diseases

Renate Viebahn‐Haensler, and Olga Sonia León Fernández Abstract: Low‐dose ozone acts as a bioregulator in chronic inflammatory diseases, biochemically characterized by high oxidative stress and a blocked regulation. During systemic applications, “Ozone peroxides” are able to replace H2O2 in its specific function of regulation, restore redox signaling, and improve the antioxidant capacity. Two different mechanisms […]

Systemic Ozone Therapy by Rectal Insufflation for Immunoglobulin A Deficiency

Jacqueline Díaz-Luis MD MS, Silvia Menéndez-Cepero PhD, Consuelo Macías-Abraham MD PhD, Lucía Fariñas-Rodríguez MS INTRODUCTION IgA defi ciency is a primary immunodeficiency predominantly due to an antibody defect, for which there is no replacement therapy. Treatment consists of prevention and treatment of infections and other associated conditions. Given the immunomodulatory and regulatory properties of the […]

Intra Articular Ozone Modulates Inflammation and Has Anabolic Effect on Knee Osteoarthritis: IL-6 and IGF-1 as Pro-Inflammatory and Anabolic Biomarkers

by Marcos E. Fernández-Cuadros 1,2,*,Olga S. Pérez-Moro 1,2,María J. Albaladejo-Florín 1,2,María M. Tobar-Izquierdo 2,3,Amelia Magaña-Sánchez 2,3,Patricia Jiménez-Cuevas 2,3 andJavier Rodríguez-de-Cía 2,3 1Servicio de Rehabilitación y Medicina Física, Hospital Universitario Santa Cristina, 28009 Madrid, Spain 2Instituto de Investigación Sanitaria del Hospital Universitario la Princesa, 28009 Madrid, Spain 3Servicio de Análisis Clínicos, Hospital Universitario Santa Cristina, 28009 Madrid, Spain Academic Editor: Gregorio Martínez Sánchez Processes2022, 10(1), 138; https://doi.org/10.3390/pr10010138Received: […]

Promising gas therapies for severe COVID-19

Ting Wang, Qian Xiang, and Jinjun Bian Journal of Intensive Medicine. 2021 Oct; 1(2): 99–102. Published online 2021 May 27. doi: 10.1016/j.jointm.2021.05.001 PMCID: PMC8157123 Abstract The novel coronavirus disease 2019 (COVID-19) pandemic is a worldwide catastrophe, thoroughly challenging the healthcare systems. A growing number of victims suffer from a remarkable acute respiratory distress syndrome (ARDS) that […]

Metanalysis on the effectiveness of low back pain treatment with oxygen-ozone mixture: Comparison between image-guided and non-image-guided injection techniques

European Journal of Radiology Open Volume 8, 2021, 100389 Abstract Low back pain (LBP) is a common disorder affecting an increasing number of people worldwide, whose diagnosis is focused on the identification of triggering causes. First line therapy usually starts from conservative approaches, whereas second line treatments include a spectrum of minimally invasive techniques, before resorting to […]

Treatment of BRONJ with ozone/oxygen therapy and debridement with piezoelectric surgery

Eur Rev Med Pharmacol Sci 2020; 24 (17): 9094-9103 F. Goker, G. Donati, F. Grecchi, A. Sparaco, M. Ghezzi, V. Rania, C.A. Rossi, M. Del Fabbro Department of Biomedical, Surgical and Dental Sciences, University of Milano, Milan, Italy. DOI: 10.26355/eurrev_202009_22855 OBJECTIVE: Bisphosphonate related osteonecrosis of the jaw (BRONJ) is progressive bone destruction in the maxillofacial region […]

Fatigue in post-acute sequelae of SARS-CoV2 (PASC) treated with oxygen-ozone autohemotherapy – preliminary results on 100 patients

U. Tirelli, M. Franzini, L. Valdenassi, S. Pisconti, R. Taibi, C. Torrisi, S. Pandolfi, S. Chirumbolo PMID: 34604980 DOI: 10.26355/eurrev_202109_26809 Abstract Objective: Post-acute sequelae of SARS-CoV2 infection (PASC) are a novel terminology used to describe post-COVID persistent symptoms, mimicking somehow the previously described chronic fatigue syndrome (CFS). In this manuscript, we evaluated a therapeutical approach to address PASC-derived […]

Safety and efficacy of ozone therapy in mild to moderate COVID-19 patients: A phase 1/11 randomized control trial (SEOT study)

2020 Siguranța și eficacitatea terapiei cu ozon la pacienții COVID-19 ușor până la moderat: Un studiu randomizat de faza I / II (studiu SEOT). Mili Shah 1, Jignasha Captain 2, Vidyadhar Vaidya 3, Arvind Kulkarni 4, Kedar Valsangkar 5, Pradeep M K Nair 6, Gayatri Ganu 7 Affiliations collapse Affiliations 1Training and Education Department, President of Ozone Forum of India, Mumbai, India. 2Head of the Clinical Department, Director of […]

Ozone therapy for the treatment of COVID-19 pneumonia: A scoping review

′′ Terapia cu ozon ar putea fi o resursă potențială pentru modularea răspunsului imunitar al pacientului împotriva SARS-CoV-2, contribuind la conţinerea stresului oxidativ celular al pneumoniei COVID-19 şi ruperea cercului vicios al furtunii citokine observate în forme severe de boala. Terapia cu ozon poate fi, de asemenea, un tratament complementar util, care trebuie luat în […]

Recent case studies on the use of ozone to combat coronavirus: Problems and perspectives

Soumya Nagashri Manjunath,a M. Sakar,b Manmohan Katapadi,a,c and R. Geetha Balakrishnab,⁎ Abstract Coronavirus pandemic has created havoc in the world. COVID-19 is now officially labeled as Severe Acute Respiratory Syndrome-related Coronavirus-SARS-CoV-2. Therefore, it is equally important to combat the virus both inside the human body as well as in the environment. These viruses, being RNA viruses, are found to […]

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