G. PELLICANÒ, F. MARTINELLI, V. TAVANTI, M. BONETTI*, M. LEONARDI**, M. MUTO***, C. ANDREULA****, N. VILLARI
Radiodiagnostics 2 Careggi University Hospital; Florence, Italy
*Neuroradiology Service, Città di Brescia Hospital; Brescia, Italy
**Neuroradiology Service, Bellaria Hospital; Bologna, Italy
***Neuroradiology Service, Cardarelli Hospital; Naples, Italy
**** Neuroradiology Unit, Anthea Hospital; Bari, Italy
SUMMARY – Oxygen-ozone therapy exploits the chemical properties of ozone, an unstable allotropic form of oxygen with the symbol O3 and a molecular weight of 48 kDa. Many biologic effects have been attributed to ozone: increased glycolysis, effects on red blood cells, effects on rheology, bactericidal, fungicide and virustatic, immunomodulating action and analgesic and anti-inflammatory effects. This broad spectrum of action explains the many indications for medical ozone administration. We assessed the results obtained in treating 15,000 patients with oxygen-ozone therapy and in particular to describe possible complications or collateral effects. The only thing we can understand is that the authors did not use correct asepsis and hygiene procedures. Hence, the low costs of oxygen-ozone therapy and the lack of any complications or collateral effects make this minimally invasive procedure safe and useful for the treatment of lumbar disc herniation.
Introduction
Oxygen-ozone intradiscal and periganglionic injection is a minimally invasive procedure first applied clinically in the peridural treatment of lumbar sciatic pain and lumbar disk herniation. A reduction in herniated disk volume is one of the therapeutic aims of the gas mixture, as disk shrinkage may reduce nerve root compression. Another reason for using medical ozone to treat disk herniation is its analgesic and anti-inflammatory effects. The transit of pure oxygen through high-voltage tubes forms ozone available for an injecting device. This type of treatment is developed to offer good clinical results combined with a well-tolerated, low cost procedure…
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