EVALUATION OF THE EFFECT OF OZONE THERAPY ON RHEUMATOID

Fourty patients with RA were selected. The patients were divided into four groups, each including ten patients as follows:

Group I :Patients suffering from old rheumatoid arthritis (> one year) and received advanced form of treatment, e.g. methotrexate, NSAIDs and corticoticosteroids. They were treated with ozone therapy as well.

Group II : Patients suffering from old rheumatoid arthritis (> one year) and received advanced form of treatment, e.g. methotrexate, NSAIDs and corticoticosteroids. They were considered as a control to group I.

Group III : Patients suffering from early rheumatoid arthritis (< 1year) and received mild form of treatment e.g. NSAIDs. They were treated with ozone therapy.

Group IV : Patients suffering from early rheumatoid arthritis (< 1year) and received mild form of treatment e.g. NSAIDs. They were considered as a control group to group III.

 

Methods

  • Ozone administration in the study groups ( I & III ) was given in the form of rectal insufflation and minor autohemotherapy at a rate of twice sessions/week for 10 weeks (Total of 20 sessions).
  • R.I. Concentration started from 15 µ/ml and increased gradually till the maximum of 40 µ/ml on the 9th session. The volume started with 250 ml and increased to 300 ml on 5th session and onwards.

 

  • Minor AHT was given in a concentration of 25 µ/ml O3 in O2 added to 5 ml of blood

 

Evaluation of the patient

This was carried on according to the ACR20 (American Collage of Rheumatology) (Felson et al., 1995)

  • ≥ 20 % improvement in painful joint count (≥28)
  • ≥ 20 % improvement in swollen joint count (≥28)
    • ≥ 20 % improvement in 3 of the following 5 areas:
    • Patient pain assessment (VAS) Visual Analogue Scale
    • Patient global assessment (PG)
    • Physician global assessment (VAS)
    • Patient self – assessed disability (AIMS, HAQ, MHIQ)
    • Acute phase reactant (ESR or CRP)

    Health Assessment Questionnaire, McMaster Health Index Questionnaire.

 

DESCARCATI TOT MATERIALUL aici

 

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